Martin Johnson, professor of reproductive science at the University of Cambridge, added: “This is a remarkable achievement, involving good quality research.
“(It is) potentially of clinical interest to those patients lacking eggs of their own.”
However some scientists said the process could be hindered by the fact that in humans eggs take more than 10 years to fully develop after birth, not maturing until puberty.
Prof Robin Lovell-Badge, group leader, The Francis Crick Institute, said “This is the first convincing evidence that it is possible to go all the way from pluripotent stem cells to functional eggs entirely [in the lab], which can then be fertilised and give rise to apparently healthy mice.
“Clearly, if applied to humans, being able to get functional eggs would have importance in overcoming female infertility, e.g. due to cancer treatment as a child, but it also opens up many other uses in research, in regenerative medicine, and potentially in avoiding genetic disease
“There is a long way to go before these methods could be adapted and used in humans. There is the question of time. It usually takes longer than a decade to have fully grown eggs in humans.
“Will it take this long to recapitulate the process in vitro, which would pose immense practical challenges, or will parts of the process speed up in vitro where the constraints that normally operate in vivo will be absent?”