• The research on stem cells published in the journal ACS Nano, also has implications for the treatment of leukaemia and breast cancer.

    SOURCE

    SEPT 2016

    Tiny bundles of stem cells built in the laboratory using microscopic magnets could pave the way to revolutionary treatments for repairing bone, cartilage, ligaments and tendons.

    The technique, developed by British scientists, overcomes one of the main obstacles to unlocking the huge medical potential of mesenchymal stem cells.

    Naturally found in the bone marrow, the stem cells have an awkward habit of spontaneously transforming into different cell types when stored outside the body.

    The University of Glasgow team overcame this problem by creating ball-shaped clumps of around 10,000 stem cells, just big enough to see with the naked eye.

    When they were placed in a soft gel with the consistency of bone marrow jelly, the cell balls remained unchanged for long periods of time and displayed no unwanted differentiated.

    Placing the 3D cultures next to laboratory “wound models” simulating damaged cartilage, bone and ligament, the stem cells re-activated. They migrated towards the injured tissue and began to develop into the right kind of cells to promote healing.

    Dr Catherine Berry, from the university’s Institute of Molecular Cell and Systems Biology, said: “This is a really exciting discovery, which uses a fairly simple and affordable method to grow and maintain stem cells ready to heal tissues.”

    To make the stem cell bundles, the team used an ingenious technique that exploits magnetism.

    Microscopic magnetic nanoparticles were first added to the stem cells, allowing them to be drawn together by the attractive force of a simple magnet.

    The research, published in the journal ACS Nano, also has implications for the treatment of leukaemia and breast cancer.

    Both diseases feature bundles of cancer stem cells that lie dormant in bone marrow for many years before re-activating and triggering disease recurrence.

    Dr Berry added: “It may be that changes in mesenchymal stem cell activity are linked to cancer cell activation.

    “We’re keen to explore how we can use our technique to understand more about how stem cells communicate with other cel

    Read more: http://www.dailymail.co.uk/wires/pa/article-3800095/Stem-cells-magnet-discovery-help-heal-bones-say-scientists.html#ixzz4L7QIK7V3
    Follow us: @MailOnline on Twitter | DailyMail on Facebook

     
     

    No comments

    Be the first one to leave a comment.

    Post a Comment


     

     

    Latest Posts

    Latest Video

     
     

    LATEST POSTS

    Chan Zuckerberg Initiative’s AI Acquisition Will Make Science Free for All

    Dr. Priscilla Chan and mark Zuckerberg. Image Credit: Chan Zuckerberg SOURCE IN BRIEF The Chan Zuckerberg initiative has taken a huge first step toward their…

    Scientists create a 3-D bioprinter to print human skin (w/video)

    SOURCE (Nanowerk News) This research has recently been published in the electronic version of the scientific journal Biofabrication (“3D bioprinting of functional human skin: production…

    Single-cell epigenomic variability reveals functional cancer heterogeneity

    Abstract Background Cell-to-cell heterogeneity is a major driver of cancer evolution, progression, and emergence of drug resistance. Epigenomic variation at the single-cell level can rapidly…

    Artificial Intelligence Predicts when heart will Fail

    Image copyrightMRC LMS Image captionThe software creates a virtual heart to predict the risk of death Artificial intelligence can predict when patients with a heart…

    Chinese surgeons use 3D printing in two landmark paediatric heart surgeries

     SOURCE Chinese surgeons have utilised 3D printing technology to perform two different paediatric heart surgeries. The surgeries took place at the Second Xiangya Hospital of Central…

    How Apps are Changing the Medical Field

      Our last article about Catalia Health and the company’s use of social robots to provide a better healthcare experience to patients created a huge…

    IBM Watson finding its way into real-world image interpretation

    Posted by admin / January 23, 2017 / Edit post Photo: Twitter user Deborah DiSanzo SOURCE A large radiology practice in the Miami area is…

    IBM uses Smartphone to to help Diagnose Melanoma

    SOURCE The smartphone is on a collision course with your local dermatologist. IBM researchers have developed a computer system that early research shows is more…